Cell subset Anti-HAV ≥20mIU/mL (n=23) Anti-HAV <20mIU/mL (n=6) Mann Whitney test (p)
CD4+ T cells(cells/mm3)
(range)
634.1
(188.1, 1295.0)
200.4
(8.7, 736.7)
0.004
Naïve: CD45RA+CCR7+ (%)
(range)
29.9
(9.7, 61.9)
20
(6.9, 30.3)
0.026
Central Memory: CD45RA-CCR7+ (%)
(range)
9.63
(3.81, 18.1)
7.13
(1.01, 17.9)
0.414
Effector Memory: CD45RA-CCR7- (%)
(range)
31.6
(14.4, 60.3)
50.2
(28.1, 68.1)
0.014
Terminally Differentiated: CD45RA+CCR7- (%)
(range)
21.7
(12.2, 55.1)
18.6
(6.8, 63.9)
0.511
Activated CD3+CD4+CD38+ HLADR+(%)
(range)
12.6
(7.9, 26.0)
24.8
(10.6 , 49.0)
0.054
CD8+ T cells (cells/mm3)
(range)
929.4
(529.9, 1852.8)
375.6
(104.0, 1633.5)
0.102
Naïve: CD45RA+CCR7+ (%)
(range)
17.2
(8.6, 52.4)
5.6
(2.2, 39.1)
0.080
Central Memory: CD45RA-CCR7+ (%)
(range)
1.2
(0,2.8)
1.8
(1,4.2)
0.694
EffectorMemory: CD45RA-CCR7- (%)
(range)
44.6
(1.7, 66)
62.6
(33.7, 78.0)
0.080
Terminally Differentiated: CD45RA+CCR7- (%)
(range)
28.5
(17.1, 89.6)
27.4
(13.8, 35.2)
0.384
Activated CD3+CD8+CD38+ HLADR+ (%)
(range)
22.0
(7.5, 59.3)
51.4
(30.8, 68.5)
0.002
B cells: CD19+ cells (cells/mm3)
(range)
334.54
(76.53, 632.7)
103.21
(6,78, 121,4)
<0.001
Immature Transitional(CD19+CD10+)(%)
(range)
33.6
(9.2, 82.9)
31.4
(10.1, 69.3)
0.655
Naive (CD21+CD27-) (%)
(range)
68.2
(37.2, 89.5)
52.1
(9.7, 69.6)
0.009
Resting Memory (CD21+CD27+) (%)
(range)
13.7
(4.6, 36.2)
9.8
(4.0, 17.4)
0.158
ActivatedMemory (CD21-CD27+)(%)
(range)
6.8
(0.7, 21.7)
18.9
(6.9, 32.8)
0.004
Exhausted Memory (CD21-CD27-) (%)
(range)
8.1
(0.4, 31.8)
22.6
(7.0, 60.7)
0.031
NK cells (cells/mm3)
(range)
209.3
(22.8, 429.3)
67.3
(35.6, 93.9)
0.002
Activated CD3-CD16+/CD56+CD38+ (%)
(range)
78.5
(49.1, 96.1)
81.8
(44.7, 99.6)
0.733
*Mann Whitney test
Table 2: Median absolute numbers and lymphocyte percentages of HIV-infected adolescents divided according to HAV seropositivity 7 years after primary immunization
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