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Figure 1: Characterization of IL-17 and IL-22-producing CD4 T cells in peripheral blood and jejunum of uninfected macaques. (A) Representative dot plots of IL-17 and/or IL-22-producing cells gated through CD3+CD4+ T cells in peripheral blood and jejunum. (B) Frequency and tissue specificity of Th17/Th22 cell subsets: percentages of IL-17+IL-22-, IL-17+IL-22+ and IL-17-IL-22+ cells in peripheral blood (n=21) and jejunum (n=42) after gating through CD3+CD4+ lymphocytes. Note the majority of IL-22+ cells from the intestine also produce IL-17, but not those from blood.
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