VACCR ICD-9
  Sensitivity PPV Sensitivity PPV
HIV+ 124/144=86% 124/131=95% 131/144=91% 131/221=59%
HIV- 95/108=88% 95/98=97% 102/108=94% 102/148=69%
Oral cavity and pharynx 3/3=100% 3/6=50% 3/3=100% 3/13=23%
Colorectal 10/11=91% 10/11=91% 10/11=91% 10/29=34%
Anal 12/16=75% 12/13=92% 13/16=81% 13/20=65%
Liver 19/22=86% 19/19=100% 20/22=91% 20/24=83%
Lung 38/48=79% 38/38=100% 45/48=94% 45/56=80%
Prostate 51/56=91% 51/52=98% 52/56=93% 52/62=84%
Non-Hodgkin lymphoma 20/21=95% 20/20=100% 21/21=100% 21/23=91%
Leukemia 9/9=100% 9/10=90% 8/9=89% 8/10=80%
Kaposi sarcoma 10/12=83% 10/10=100% 12/12=100% 12/15=80%
Other specified cancers† 45/51=88% 45/46=98% 47/51=92% 47/89=53%
Cancers of unspecified site 2/3=67% 2/4=50% 2/3=67% 2/28=7%
*Cancer types with at least 10 VACCR or ICD-9 code diagnoses
†Cancer-type specific sensitivity and PPV for the following cancer types combined: esophagus, stomach, small intestine, biliary tract, pancreas, peritoneum and
retroperitoneum, larynx, pleura, melanoma, breast, uterus or corpus, penis, testicular, bladder, kidney, brain and nervous system, thyroid, Hodgkin lymphoma, multiple myeloma
Table 3: Sensitivity and positive predictive value (PPV) of Veterans Affairs Central Cancer Registry (VACCR) and ICD-9 code diagnoses by HIV status and for common cancer types* (chart review as gold standard).
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