| Characteristics |
Naive* patients |
Experienced patients |
| |
Without co-infection (N=195) |
With co-infection (N=61) |
P** |
Without co-infection (N=624) |
With co-infection (N=399) |
P** |
| Sex |
| Male |
138 (70.8%) |
42 (68.9%) |
0,77 |
427 (68.4%) |
293 (73.4%) |
0,09 |
| Age in years |
| Median (range) |
39 (18-82) |
41 (21-66) |
|
42 (18-79) |
43 (22-79) |
|
| Time from HIV-positive in years |
| Median (range) |
1 (0-20) |
7.2 (0-24.3) |
<0,0001 |
11(0-23.3) |
15.2 (0.1-25.3) |
<0,0001 |
| CDC classification C |
|
|
|
|
|
|
| Yes |
39(20%) |
12 (19.7%) |
0,96 |
204 (32.7%) |
123 (30.8%) |
0,53 |
| HIV-1 RNA log10 copies per mL |
| Mean (±SD) |
5.2 (± 0.8) |
4.8 (± 0.9) |
<0.01 |
3.3 (± 1.5) |
3.3 (± 1.5) |
0.65 |
| >5 log10 copies per mL |
109 (65.3%) |
23(50%) |
0.06 |
99 (15.9%) |
62 (15.5%) |
0.89 |
| Missing value |
28 |
15 |
|
0 |
0 |
|
| CD4+ cell count in cells per mL |
| Mean (±SD) |
210(±140) |
197.7 (±164.5) |
0.61 |
394.3 (±251.7) |
341(±244.7) |
<0.0001 |
| Missing value |
26 |
16 |
|
5 |
5 |
|
| ALT Grade |
|
|
|
|
|
| Normal |
102 (81%) |
32 (80%) |
0,91** |
414 (83.5%) |
188 (58%) |
<0,001 |
| Grade 1/2 |
22 (17.5%) |
7 (17.5%) |
|
77(15.5%) |
127(39.2%) |
|
| Grade 3/4 |
2(1.6%) |
1 (2.5%) |
|
5(1%) |
9(2.8%) |
|
| Missing |
69 |
21 |
|
128 |
75 |
|
| AST Grade |
| Normal |
107 (84.9%) |
27 (67.5%) |
0.02** |
433 (87.2%) |
167 (51.3%) |
<0.001 |
| Grade 1/2 |
18(13.3%) |
11 (28%) |
|
57(11.5%) |
149 (45.8%) |
|
| Grade 3/4 |
1 (0.8%) |
2 (5%) |
|
6(1.2%) |
9(2.8%) |
|
| Missing |
69 |
21 |
|
128 |
74 |
|
|
