Variable Crude Analysis Adjusted Analysis*
Odds Ratio  (95% CI)      P value Odds Ratio (95% CI)      P value
Age in years 1.0 (0.95-1.04) 0.8 - -
Race/Ethnicity
Non-hispanic white Reference - - -
Non-hispanic black 1.52 (0.47-4.9) - - -
Other 1.33 (0.18-9.73) 0.78 - -
Weight in Kg 0.99 (0.97-1.01) 0.33   0.99 (0.96-1.01) 0.24
Gender
Male Reference - - -
Female 0.5 (0.15-1.66) 0.26 - -
TDF stopped
No Reference - - -
Yes 2.54 (0.97-6.64) 0.06 3.76 (1.26-11.27) 0.02
Increase in sCr ≥0.3 mg/dl 1.00 (0.87-1.15) 0.97 0.75 (0.45-1.23) 0.25
Baseline CKD1
No Reference - - -
Yes 0.16 (0.04-0.68) 0.01 -  
HCV Antibody
Negative Reference - - -
Positive 2.32 (0.69-7.81) 0.18 - -
Diabetes Mellitus
No Reference   Reference  
Yes 0.63 (0.18-2.2) 0.46 0.29 (0.06-1.48) 0.14
Hypertension
No Reference   Reference  
Yes 1.09 (0.42-2.81) 0.86 1.59 (0.45-5.66) 0.47
Nephrotoxic drugs
No Reference   Reference  
Yes 1.16 (0.46–2.96) 0.76 1.34 (0.43-4.21) 0.61
HIV-1 PVL2
≤75 log10 copies/ml Reference      
>75 log10 copies/ml 0.52 (0.18-1.54) 0.24    
CD4 cell count2
≤200 cells/µL Reference      
>200 cells/µL 0.86 (0.33-2.21) 0.75    
Table 2: Crude and Adjusted Analysis: Factors Associated with Renal Function Recovery. 1Adjusted not performed given small number of cases (n = 10); 2At time of HLA test; *Observations with missing data were excluded from analysis. TDF: Tenofovir; sCr: Serum Creatinine; HCV: Hepatitis C Virus; PVL: Plasma Viral Load.
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