| Characteristics |
Men |
Women |
P-value |
| |
n=97 |
n=96 |
|
| Mean age (SD), years |
57.2 (5.8) |
58.0 (5.9) |
0.34 |
| Mean weight (SD), kg |
64.5 (11.0) |
65.5 (13.5) |
0.57 |
| Mean height (SD), cm |
176 (8) |
163 (7) |
<0.001 |
| Mean BMI (SD), kg/m2 |
20.8 (3.4) |
24.5 (4.5) |
<0.001 |
| Underweight |
28 (29%) |
11 (11%) |
<0.001 |
| Normal |
60 (62%) |
42 (44%) |
| Overweight |
8 (8%) |
30 (31%) |
| Obesity |
1 (1%) |
13 (14%) |
| At least one risk factor |
29 (30%) |
12 (13%) |
0.003 |
| Previous fracture |
7 (7%) |
5 (5%) |
0.77 |
| Parent fractured hip |
4 (4%) |
5 (5%) |
0.75 |
| Currentsmoker |
17 (18%) |
1 (1%) |
<0.001 |
| Alcohol(≥ 3 units/day) |
3 (3%) |
0 |
0.25 |
| Corticosteroid use |
0 |
1 (1%) |
0.50 |
| Rheumatoidarthritis |
0 |
2 (2%) |
0.25 |
| Secondaryosteoporosis |
4 (4%) |
1 (1%) |
0.37 |
| Post-menopausal (n=94) |
|
93 (99%) |
|
| Physicalactivity |
|
|
|
| Low |
26 (27%) |
36 (38%) |
<0.001 |
| Moderate |
38 (39%) |
50 (52%) |
| High |
33 (34%) |
10 (10%) |
| |
|
|
|
| Median ART duration (IQR), years |
7.2 (4.0-10.4) |
5.7 (3.6-8.8) |
0.16 |
| Current PI use |
16 (16%) |
20 (21%) |
0.44 |
| Current TDF use |
22 (23%) |
24 (25%) |
0.71 |
| Median CD4 count nadir (IQR), cells/μLa |
108 (47-190) |
144 (81-243) |
0.029 |
| CD4 count nadir<200 cells/μL* |
72 (77%) |
61 (66%) |
0.12 |
| Median current CD4 count (IQR), cells/μLa |
422 (294-588) |
470 (346-722) |
0.13 |
| CD4 cell count<350 cells/μLa |
29 (37%) |
17 (25%) |
0.13 |
| Undetectable viral loada |
37 (82%) |
33 (87%) |
0.56 |
SD: Standard Deviation; BMI: Body Mass Index; ART: Antiretroviral Treatment;
IQR: Interquartile Range; PI: Protease Inhibitor; TDF: Tenofovir Disoproxyl
Fumarate
aCD cell count, CD4 nadir and viral load were available for 145, 186 and 83
subjects respectively. |
