HCV- (n=224) HCV+ (n=84) P value
Age, yrs, median (IQR) 45.0 (38.9, 51.5) 53.1 (49.5, 56.6) <0.0001*
Race/ethnicity, n (%)     0.22§
White non-Hispanic 40 (17.9) 10 (11.9)  
Black non-Hispanic 143 (63.8) 64 (76.2)  
Hispanic 27 (12.1) 8 (9.5)  
Other 14 (6.2) 2 (2.4)  
Alcohol use, n (%)     0.069#
Abstainer (no drinks) 100 (44.6) 39 (46.4)  
Light (<3 drinks/week) 61 (27.2) 19 (22.6)  
Moderate (3-13 drinks/week) 35 (15.6) 7 (8.3)  
Heavier (≥14 drinks/week) 24 (10.7) 17 (20.2)  
Smoker, n (%)     <0.0001#
Never 70 (31.3) 8 (9.5)  
Current 84 (37.5) 57 (67.9)  
Former 70 (31.3) 19 (22.6)  
Ever injected drug use, n (%) 28 (12.5) 67 (79.8) <0.0001#
BMI, median (IQR) 25.6 (22.6, 28.7) 25.7 (21.9, 28.8) 0.83*
HIV status, n (%)     0.020#
Positive 167 (74.6) 73 (86.9)  
Negative 57 (25.4) 11 (13.1)  
HCV RNA´103 IU/ml, median (IQR) / 2020 (651, 4020) /
Ever HCV medication / 17 (20.2) /
AST, IU/L, median (IQR) 20 (16, 25) 38.5 (28.5, 71.5) <0.0001*
ALT, IU/L, median (IQR) 16 (11, 23) 29 (20.5, 48) <0.0001*
Platelets, ´103/µl, median (IQR) 237.5 (203, 280.5) 193.5 (157.5, 228.5) <0.0001*
Platelets<150´103/µl, n (%) 9 (4.0) 20 (23.8) <0.0001#
Albumin (g/L) 4.3 (4.1, 4.5) 4.0 (3.7, 4.3) <0.0001*
HA, ng/mL, median (IQR) 22 (12.5, 38) 55.5 (31, 114) <0.0001*
SHASTA, median (IQR) 0.02 (0.02, 0.02) 0.11 (0.02, 0.41) <0.0001*
APRI, median (IQR) 0.26 (0.20, 0.33) 0.54 (0.38, 1.17) <0.0001*
METAVIR stage using TE cutpoints, n (%)     <0.0001§
F0-1 202 (90.2) 45 (53.6)  
F2 15 (6.7) 13 (15.5)  
F3 3 (1.3) 10 (11.9)  
F4 4 (1.8) 16 (19.0)  
IQR: Interquartile Range; AST: Aspartate Aminotransferase; ALT: Alanine Aminotransferase; HA: Hyaluronic Acid; APRI: AST to Platelet Ratio Index
*Wilcoxon-Mann-Whitney test
#Chi-square test
§Fisher exact test
Table 1: Characteristics by HCV status among the 308 WIHS women.
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