|  | Annualised rate of change (%) | 
      
        | 2000–2013 | 
      
        |  | Incidence | Prevalence | Mortality | 
      
        | Worldwide | −0·60 (−0·73 to −0·50) | −1·31 (−1·41 to −1·20) | −3·72 (−4·42 to −2·99) | 
      
        | High-income Asia Pacific | 0·11 (−0·06 to 0·27) | 0·13 (−0·18 to 0·40) | −5·03 (−5·85 to −3·99) | 
      
        | Central Asia | −0·76 (−0·92 to −0·58) | −0·68 (−0·85 to −0·50) | −4·97 (−5·83 to −4·07) | 
      
        | East Asia | −2·08 (−2·36 to −1·85) | −3·16 (−3·44 to −2·86) | −7·54 (−8·53 to −6·63) | 
      
        | South Asia | −1·06 (−1·30 to −0·80) | −2·43 (−2·65 to −2·20) | −4·22 (−5·64 to −2·89) | 
      
        | Southeast Asia | −0·54 (−0·68 to −0·42) | 0·12 (−0·03 to 0·28) | −3·61 (−4·42 to −2·82) | 
      
        | Australasia | −0·22 (−0·41 to −0·03) | −0·36 (−0·66 to −0·08) | −3·63 (−4·62 to −2·62) | 
      
        | Caribbean | −0·20 (−0·35 to −0·05) | −1·15 (−1·32 to −0·98) | −3·93 (−4·93 to −2·50) | 
      
        | Central Europe | −1·61 (−1·74 to −1·50) | −0·29 (−0·42 to −0·17) | −5·95 (−6·43 to −5·27) | 
      
        | Eastern Europe | −0·58 (−0·80 to −0·39) | −0·75 (−0·97 to −0·53) | −4·80 (−7·62 to −3·91) | 
      
        | Western Europe | −1·18 (−1·28 to −1·08) | −0·64 (−0·78 to −0·52) | −4·88 (−5·53 to −3·78) | 
      
        | Andean Latin America | −0·81 (−1·04 to −0·54) | −0·78 (−1·06 to −0·52) | −4·86 (−5·88 to −3·78) | 
      
        | Central Latin America | −1·69 (−1·83 to −1·55) | −1·51 (−1·67 to −1·35) | −4·21 (−4·74 to −3·03) | 
      
        | Southern Latin America | −2·56 (−2·75 to −2·39) | −1·56 (−1·78 to −1·32) | −3·35 (−4·03 to −2·70) | 
      
        | Tropical Latin America | −1·27 (−1·50 to −1·08) | −0·68 (−1·04 to −0·36) | −4·33 (−5·36 to −3·47) | 
      
        | North Africa and Middle East | −1·10 (−1·18 to −1·03) | −1·26 (−1·35 to −1·16) | −4·58 (−5·34 to −3·89) | 
      
        | High-income North America | −3·32 (−3·55 to −3·10) | −2·28 (−2·57 to −1·97) | −4·14 (−5·14 to −1·90) | 
      
        | Oceania | 0·77 (0·60 to 0·98) | 0·14 (−0·09 to 0·37) | −2·96 (−4·58 to −0·91) | 
      
        | Central sub-Saharan Africa | 0·07 (−0·12 to 0·28) | −0·17 (−0·41 to 0·06) | −3·41 (−4·67 to −1·99) | 
      
        | Eastern sub-Saharan Africa | −0·34 (−0·52 to −0·16) | −0·38 (−0·57 to −0·20) | −3·08 (−4·12 to −2·40) | 
      
        | Southern sub-Saharan Africa | 0·14 (−0·26 to 0·54) | −0·09 (−0·41 to 0·28) | −4·12 (−5·91 to −2·91) | 
      
        | Western sub-Saharan Africa | −0·57 (−0·73 to −0·39) | −0·69 (−0·86 to −0·49) | −3·09 (−3·84 to −2·17) |