Geometric mean value (95% Confidence Interval) Number above upper limit of normal/number evaluated (%) p value
HIV positive HIV negative p value HIV positive HIV negative
Bile acids (μmol/L)
Entry1 4.96
(3.63, 6.76)
4.75
(4.05, 5.56)
0.798 7/20
(35.00)
10/23
(43.48)
0.571
Last pregnancy visit2 4.04
(3.43, 4.76)
4.45
(3.49, 5.68)
0.494 2/21
(9.52)
2/21
(9.52)
1.0
Post-partum3 4.73
(3.40, 6.59)
5.16
(4.18, 6.38)
0.639 6/14
(42.86)
11/18
(61.11)
0.305
Aspartatetransaminase (AST; U/L)
Entry 16.2
(12.85, 20.42)
22.5
(20.07, 25.13)
0.013 2/20
(10.00)
6/22
(27.27)
0.155
Last pregnancy visit 20.4
(15.93, 26.18)
24.0
(22.38, 25.76)
0.202 3/19
(15.79)
1/21
(4.76)
0.246
Post-partum 23.7
(17.26, 32.47)
27.7
(23.11, 33.26)
0.362 2/14
(14.29)
4/17
(23.53)
0.517
Alanine transaminase (ALT; U/L)
Entry 19.5
(14.57, 26.07)
19.6
(16.27, 23.65)
0.968 4/20
(20.00)
2/22
(9.09)
0.313
Last pregnancy visit 22.0
(16.38, 29.50)
18.0
(15.40, 20.95)
0.213 4/19
(21.05)
1/21
(4.76)
0.12
Post-partum 30.9
(22.81, 41.75)
29.5
(21.83, 39.81)
0.82 4/14
(28.57)
4/17
(23.53)
0.75
γ-glutamiltranspeptidase(GGT; U/L)
Entry 15.7
(8.03, 30.73)
11.0
(9.66, 12.47)
0.284 4/19
(21.05)
0/22
(0.00)
0.023
Last pregnancy visit 17.0
(7.80, 36.85)
10.8
(8.66, 13.55)
0.255 6/17
(35.29)
1/20
(5.00)
0.019
Post-partum 23.3
(13.67, 39.77)
13.2
(10.99, 15.79)
0.044 1/11
(9.09%)
0/17
(0.00)
0.206
Total bilirubin (mg/dL)
Entry 0.3
(0.24, 0.55)
0.59
(0.48, 0.72)
0.041 3/20
(15.00)
16/22
(72.73)
<0.001
Last pregnancy visit 0.42
(0.29, 0.62)
0.61
(0.51, 0.73)
0.077 2/19
(10.53)
7/21
(33.33)
0.085
Post-partum 0.56
(0.36, 0.88)
0.71
(0.57, 0.89)
0.321 1/13
(7.69)
0/17
(0.00)
0.245
1Median (IQR) gestational age = 21.4 (19.5-24.5) weeks
2Median (IQR) gestational age = 36.0 (33.0-37.0) weeks
3Median (IQR) time after delivery = 7.4 (5.6-12.1) weeks
Table 2: Maternal bile acids and liver function values during pregnancy and post-partum.
Goto home»