| |
Naïve patients
(N=407) |
Switch
(N=696) |
Failure
(N=601) |
| Treatment duration before discontinuation |
[0-6[ months
(N=93) |
≥ 6 months
(N=55) |
Total
(N=148) |
[0-6[ months
(N=93) |
≥ 6 months (N=73) |
Total
(N=166) |
[0-6[ months
(N=120) |
≥ 6 months
(N=131) |
Total
(N=251) |
| Intolerance, N (%) |
47 (11.5) |
9 (2.5) |
56 (14) |
68 (10) |
22 (3) |
90 (13) |
65 (11) |
23 (4) |
88 (15) |
| Suspected hypersensitivity, N (%) |
27 (6.6) |
3 (0.7) |
30 (7.3) |
40 (5.7) |
2 (0.3) |
42 (6) |
46 (7.6) |
2 (0.3) |
48 (7.9) |
| Treatment failure, N (%) |
6 (2) |
17 (4) |
23 (6) |
2 (1) |
16 (2) |
18 (3) |
7 (1) |
66 (11) |
73 (12) |
| Other, including non adherence, N (%) |
40 (10) |
29 (7) |
69 (17) |
23 (3.3) |
35 (5) |
58 (8.3) |
48 (8) |
42 (7) |
90 (15) |
|
