P no. Xolair Dose Skin test sensitivity SSTa Allergic Reaction Number of Injection Efficacy of Omalizumab
1 375 mg q. 2 wk Grass, tree, mold, mite - Aller rhin conj, AD 78 dose 3: AD and NSS improved significantly
2 225 mg q. 2 wk Grass, mite, cockroach + Aller rhin conj, NP, MD Aller, angioedema and UC 72 dose 5: improvement in UC and angioedema attacks and NSS decreased
3 225 mg q. 2 wk Grass, wheat, tree, mold, mite, cockroach, dog and cat epithelium - Aller rhin conj, NP 63 dose 3: improvement in NSS
4 300 mg q. 2 wk Grass, wheat, tree, mold, mite, cockroach, honeybee, dog and cat epithelium - Aller rhin conj, NP venom aller, bee-sting anaphylaxis and UC 68 dose 1: decrease in NSS, dose 3: improvement in UC, dose 12: no anaphylactic reaction after 48 honey bee-sting.
5 300 mg q. 2 wk mold, mite, cockroach, tomato, eggplant, strawberry, dog epithelium - Aller rhin conj, NP, food aller and anaphylaxis (food. induced) 64 dose 1: improvement in NSS
dose 6: tolerated food allergy and no food induced UC
6 300 mg q. 2 wk Grass, tree, mite, shrimp, perch, egg and latex + Aller rhin conj, NP, MD aller, food aller, latex aller, anaphylaxis (NSAID induced) and AD 72 dose 1: NSS decreased
dose 5: AD and food allergy improved significantly
dose 10: improvement in UC and angioedema attacks
7 300 mg q. 2 wk wheat, tree, mite - Aller rhin conj, NP, MD Aller and AD dermatitis 74 dose 3: improvement in NSS
dose 5: improvement in UC
8 300 mg q. 2 wk Grass, tree, mite, kiwi and orange - Aller rhin conj, NP, MD aller, food aller 76 dose 3: Improvement in UC attacks, NSS and F aller.
9

225 mg q. 2 wk

Grass, wheat, tree, mold, mite, cockroach, honeybee, dog and cat epithelium - Aller rhin conj, NP, MD Aller, venom aller and AD 72 dose 2: NSS improved
dose 4: no exacerbation in AD
10 300mg q. 2 wk Grass, mold,
mite,
cockroach
- Aller rhin conj, MD aller, UC 64 dose 4: improvement in UC attacks, NSS
11 300mg q. 2 wk Grass, tree,
mite, dog epitelia
- Aller rhin conj and AD

 

68 dose 2: NSS improves
dose 6: no exacerbation in AD
AD: Atopic Dermatitis; Aller: Allergy; Conj: Conjunctivitis; MD: mMultidrug; NP: Nasal Polyp; NSAID: Non-Steroidal Anti-Inflammatory Drug; NSS: Nasal Symptom Scoring; P: Patient; Rhin: Rhinitis; SSTa: Autologous Serum Skin Test; UC: Urticarial
Table 2: Clinical follow-up criteria and changes with omalizumab.
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