Patient |
AIT |
NSAID |
Time of NSAID |
Timing and Nature of Reaction |
Management |
Continued Treatment? |
A |
dust mite, cat, grass, tree |
ibuprofen |
Morning of injection |
1 hour post-injection
Diffuse urticaria, shortness of breath |
Epinephrine 0.3 mg IM |
No |
B |
dust mite, cat, grass, tree |
ibuprofen |
Daily x 1 week prior to injection |
5 minutes post-injection
Presyncope, nausea, vomiting, hypotension |
Epinephrine 0.3 mg IM x 2
Epinephrine 0.5 mg IM x 1 |
No |
C |
Preseasonal trees & grasses |
ibuprofen |
Morning of injection |
Two hours post-injection
Diffuse urticaria, throat discomfort |
Epinephrine 0.3 mg IM
Cetirizine 20 mg PO |
Yes |
D |
cat |
ibuprofen |
Night prior and morning of injection |
Two hours post-injection
Diffuse urticaria, angioedema, chest tightness |
Loratadine 10 mg PO |
Yes |
E |
cat |
ibuprofen |
Two hours prior to injection |
15 minutes post-injection Diffuse urticaria, angioedema, shortness of breath |
Epinephrine 0.3 mg IM
Epinephrine 0.15 mg IM
Cetirizine 20 mg PO |
Yes |
F |
dust mite, cat |
ASA |
Morning of injection |
15 minutes post-injection
Diffuse urticaria, shortness of breath |
Epinephrine 0.3 mg IM |
Yes |