Patient AIT NSAID Time of NSAID Timing and Nature of Reaction Management Continued Treatment?
A dust mite, cat, grass, tree ibuprofen Morning of injection 1 hour post-injection
Diffuse urticaria, shortness of breath
Epinephrine 0.3 mg IM No
B dust mite, cat, grass, tree ibuprofen Daily x 1 week prior to injection 5 minutes post-injection
Presyncope, nausea, vomiting, hypotension
Epinephrine 0.3 mg IM x 2
Epinephrine 0.5 mg IM x 1
No
C Preseasonal trees & grasses ibuprofen Morning of injection Two hours post-injection
Diffuse urticaria, throat discomfort
Epinephrine 0.3 mg IM
Cetirizine 20 mg PO
Yes
D cat ibuprofen Night prior and morning of injection Two hours post-injection
Diffuse urticaria, angioedema, chest tightness
Loratadine 10 mg PO Yes
E cat ibuprofen Two hours prior to injection 15 minutes post-injection Diffuse urticaria, angioedema, shortness of breath Epinephrine 0.3 mg IM
Epinephrine 0.15 mg IM
Cetirizine 20 mg PO
Yes
F dust mite, cat ASA Morning of injection 15 minutes post-injection
Diffuse urticaria, shortness of breath
Epinephrine 0.3 mg IM Yes
Table 1: Summary of Anaphylaxis Cases.
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