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Figure 2: Effect of administration of Freund´s Adjuvants (FA) via either i.m or s.c routes in the levels of IL-1β, TNFα and IFNγ in serum of mice Balb/c. The serum levels of IL-1β, TNFα and IFNγ were measured in all treated groups and controls. Mice (n=5) were bled at 14th, 8 h after application of FA and before administration of APAP. Serum was pooled from each group and measured serum cytokine profile in triplicates by ELISA. |