Figure 7: Selected histological images of the livers after oral administration of Acetaminophen (APAP) in normal or treated mice with Freund´s Adjuvants (FA). Representative images of macroscopic (upper panels) and microscopic (lower panel) pathological findings. (A) Vehicle control group (×100), (B) APAP treated group, (arrow indicates a focus of hepatic necrosis) (×400),(C) APAP plus FA treatment group (×400). Livers from mice treated with FA without APAP did not show any damage (not shown).
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