Treatment type Dose dependent, time to onset
Topical corticosteroids 1-2 weeks
Topical retinoids 2-4 weeks
Topical calcineurin inhibitors 8 weeks
Phototherapy or sunlight exposure 1-3 months
Oral prednisone 1-2 weeks
Cyclosporine 3-6 weeks
Methotrexate 6-8 weeks
TNF-alpha inhibitors 1-3 months
Oral retinoids 2-3 months
Mycophenolate mofetil Up to 3 months
Azathioprine 2-6 months
Table 1: ACD Treatment Duration to Effect Onset [6,25,26].
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