Scale Result
0 The allergic reaction was equal to the negative control reaction
+ The mean wheal diameter was higher than the allergenic reaction to the negative control fluid, and less than half of the mean histamine wheal diameter
++ The mean allergic wheal diameter was equal to or greater than half of the mean histamine wheal diameter
+++ The mean allergic wheal diameter was equal to or greater than the mean histamine wheal diameter
++++ The mean allergic wheal diameter was at least two-fold greater than the mean histamine wheal diameter or every reaction with pseudopodia
Another plus was added with each doubling of the mean allergic wheal diameter in relation to the histamine reaction.
Table 3: The results of allergic reaction using the `+` scale.
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