Author, year Allergen Active/placebo Duration Jadad score Main results
Hirsch, 1997 Mite 13/14 1 yr 5/5 ↓ asthma symptom score; no change in bronchial reactivity
Niu, 2006 Mite 56/54 6 mo 4/5 ↓ asthma symptom score, daytime, nighttime symptoms and  medication score; no change FEV1 and oral steroids
Lue, 2006 Mite 10/10 8 mo 4/5 ↓ nighttime symptoms, ↑FEV1 vs baseline; no change total symptom score, medications and FEV1 vs placebo
Dahl, 2006 Grass 74/40 5 mo 5/5 no change symptoms and medications
Pham Ti, 2007 Mite 55/56 18 mo 4/5 no change symptoms, medications, FEV1, well days
Stelmach, 2009 Grass 25/25 2 season 5/5 ↓ asthma symptoms and medications
Bufe, 2009 Grass 126/127 6 mo 5/5 ↓ asthma symptoms; no change medications
↓: decrease/reduction; ↑: increase; FEV1: Forced Expiratory Volume in one second; PEFR: Peak Expiratory Flow Rate; QoL: Quality of Life.
Table 1: The most recent randomized controlled trials of SLIT considering also asthma symptoms in patients with concomitant rhinitis.
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