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| Figure 3: Levels of proinflammatory cytokines and chemokines in the BAL of WT and cav-1-/- mice Cytokine and chemokine levels in the BAL were measured by Multiplex. cav-1-/- mice (cav-1-/- LPS) had increased cytokine and chemokine levels following LPS exposure including A) MIP-1a, B) IL-6, C) IL-1β, and D) TNF-a in their BAL compared to WT mice (WT LPS). There were no differences in cytokine and chemokine levels in the BAL of PBS treated WT and cav-1-/- mice (WT sham and cav-1-/- sham), which were used as controls (***, p < 0.001, **, p < 0.01, n = 8 – 11). |
