Skin tissue samples were collected at various time points after E (filled bar), E/Dex (gray bar), or Sa (open bar) injection. Relative expression levels of mRNA of hyaluronan synthase (HAS)-1 (A), -2 (B), -3 (C), and versican (Vcan; D), were analyzed as described in Materials and Methods. The values are means ± SD (n = 6). *P < 0.05; **P < 0.01; ***P < 0.005.
