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Figure 3: Demonstration of enhanced selectivity resulting from the use of narrow mass tolerance windows for 100ng/ml captopril DBS (red), blank DBS (blue), and 903 sampling card extract (black). EIC of the protonated captopril at m/z 218.0845 using mass tolerance filters of (a) ± 500ppm (b) ± 100ppm and (c) ±1ppm. |