Metals/ Parameters Oral RFD
(µg/kg/day)
Recommended Daily Oral Dose* PDE (µg/day) Oral Component Limit (OCL) (µg/g) Parenteral Component Limit (PCL)   (µg/g)
Chromium 5 250 25 2.5
Mercury 0.3 15 1.5 0.15
Lead 0.2 10 1 0.1
Nickel 5 250 25 2.5
Arsenic 0.3 15 1.5 0.15
Cadmium 0.1 5 0.5 0.05
*Recommended daily oral dose based on a 50 kg person
Table 3: Elemental Impurities Guidelines (DeStefano et al, 2010).
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