Group |
Parameter |
Human subjects |
Group |
Parameter |
Experimental animals |
Control |
Lead exposed |
Control |
Low dose exposure (2000 ppm) |
High dose exposure (4000 ppm) |
MDA( nmol/dl) |
18.73 ± 7.4 |
39.68a ± 2.84 |
MDA (nmol/g) |
4.30 ± 2.18 |
9.52a
± 2.26 |
24.16a,b
± 4.13 |
GSH (mg/dl) |
34.5 ± 7 |
12.6a ± 4.75 |
GSH (mg/g) |
12.97 ± 0.87 |
24.57a ± 6.74 |
10.94b ± 2.77 |
SOD (U/dl) |
5.46 ± 0.43 |
4.16 ± 0.22 |
SOD (U/g) |
34.5 ± 1.6 |
28.5 ±1.6 |
21.4a,b ± 2.1 |
Results are presented as means ± SD (n=8 for each mice group and 15 for human group)
a=Significant difference (P<0.05) comparing to the normal control group (mice or human)
b=Significant difference (P<0.05) comparing to 2000 ppm lead acetate (low dose) group |