Control rats Treated rats   NC DC Effect DT400 Effect DT800 Effect Body weight (g) 157.13 ± 2.30 325.50 ± 2.73** ⇑ 336.00 ± 3.76 ⇔ 322.40 ± 3.85 ⇔ Glucose (mg/dl) 133.72 ± 2.08 614.85 ± 3.84** ⇑ 432.55 ± 15.49* ⇓ 323.96 ± 4.89* ⇓ HbA1c (%) 3.38 ± 0.12 12.59 ± 0.12** ⇑ 09.98 ± 0.79 ⇓ 11.58 ± 0.67 ⇔ Insulin (pmol/l) 50.31 ± 0.99 184.85 ± 1.28** ⇑ 162.66 ± 0.83* ⇓ 158.98 ± 1.76* ⇓ HOMA-IR 2.34 ± 0.98 40.35 ± 2.02** ⇑ 32.38 ± 1.65* ⇓ 13.78 ± 1.39* ⇓⇓ TC (mg/dl) 75.95 ± 1.17 208.87 ± 1.37** ⇑ 159.85 ± 2.65* ⇓ 202.29 ± 2.48 ⇔ TGs (mg/dl) 60.25 ± 0.71 418.06 ± 3.19** ⇑ 274.87 ± 2.59* ⇓ 398.95 ± 3.73 ⇔ Results are mean±SEM of 6 rats per each group. Statistically significant differences are indicated by the symbols: * versus normal control rat group and ** versus diabetic control rat group. p< 0.001

Table 2: Effect of CCEO essential oil on body weight, glucose, HbA1c, insulin, HOMA-IR and lipid profiles (TC and TGs) on different rat groups.

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