Binding Antibodies
Total
LD
MD
HD
Day 15 (week 2
67% (+)
25% (+)
87% (+)
92% (+)
Day 29 (week 5
100% (+)
100% (+)
100% (+)
100% (+)
Day 43 (week 7
100% (+)
100% (+)
100% (+)
100% (+)
Day 85 (week 13
100% (+)
100% (+)
100% (+)
100% (+)
Neutralizing Antibodies
Day 15 (week 2
52% (+)
Day 29 (week 5)
96% (+)
Day 43 (week 7)
89% (+)
Table 1:
Determination of binding (ADAs) and neutralizing antibodies in non human primates treated with PEG-IFNα-2B during 13 weeks by the subcutaneous route. LD: Low Dose; MD: Mid Dose; HD: High Dose.
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