Cell Lines

Hsp90α mRNA/100 ng cells extract (1 x 106 cells)

% cells expressing Hsp90α

% Akt/PKB kinase activity

Control

      

1321N1

99772

78

100

GOS-3

95945

67

100

U87-MG

96292

81

100

siRNA

 

 

 

1321N1

65973

51

14.97

GOS-3

75123

52

45.6

U87-MG

48204

41

27.29

shRNA

 

 

 

1321N1

46856

37

0.58

GOS-3

29623

21

7.87

U87-MG

32482

28

0.32
Data values are mean ± standard deviation, n=3
Table 1: A comparison between siRNA vs shRNA in three glioma cell lines.
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