| Study groups |
N * |
GG vs. AA |
GA vs. AA |
GG/GA vs. AA |
GG vs. GA/AA |
G vs. A |
| OR (95% CI) |
P﹩ |
OR (95% CI) |
P﹩ |
OR (95% CI) |
P﹩ |
OR (95% CI) |
P﹩ |
OR (95% CI) |
P﹩ |
| Total |
17 |
1.217 (0.923-1.605) ‡ |
<0.001 |
1.161 (0.991-1.360)‡ |
<0.001 |
1.165 (0.932-1.456)‡ |
<0.001 |
1.114 (0.948-1.312)‡ |
<0.001 |
0.966 (0.829-1.126)‡ |
<0.001 |
| Cancer type |
|
|
|
|
|
|
|
|
|
|
|
| Hepatocellular |
2 |
1.433 (1.100-1.866) |
0.851 |
1.291 (0.992-1.681) |
0.771 |
1.360 (1.059-1.746) |
0.796 |
1.168 (0.996-1.367) |
0.920 |
0.857 (0.761-0.964) |
0.983 |
| Gastric |
4 |
1.160 (0.601-2.237)‡ |
<0.001 |
1.300 (0.670-2.521)‡ |
<0.001 |
1.235 (0.662-2.302)‡ |
<0.001 |
1.077 (0.814 -1.508) ‡ |
0.042 |
1.033 (0.696-1.532)‡ |
<0.001 |
| Colorectal |
5 |
1.028 (0.479-2.207)‡ |
0.020 |
0.805 (0.498- 1.301)‡ |
0.006 |
0.858 (0.543-1.354)‡ |
0.006 |
1.079 (0.804-1.447) |
0.215 |
0.929 (0.727-1.188)‡ |
0.060 |
| Esophagus |
2 |
1.004 (0.235-4.295)‡ |
<0.001 |
1.454 (1.110-1.906) |
0.146 |
1.194 (0.482-2.957)‡ |
0.002 |
0.809 (0.273-2.398)‡ |
<0.001 |
0.708 (0.627-0.799) |
0.368 |
| Oral |
2 |
0.725 (0.379-1.385) |
0.312 |
1.086 (0.259-4.554)‡ |
0.013 |
1.017 (0.300-3.449)‡ |
0.026 |
0.876 (0.563-1.364) |
0.478 |
1.058 (0.786-1.424) |
0.240 |
| Pancreatic |
2 |
1.976 (1.496-2.611) |
0.173 |
1.433 (1.093-1.879) |
0.766 |
1.668 (1.286-2.164) |
0.347 |
1.502 (1.098-2.054)‡ |
0.033 |
1.394 (1.098-1.770)‡ |
0.049 |
| Ethnicity |
|
|
|
|
|
|
|
|
|
|
|
| Asian |
12 |
1.240 (0.908-1.695)‡ |
<0.001 |
1.164 (0.895- 1.514)‡ |
<0.001 |
1.179(0.896-1.551)‡ |
<0.001 |
1.139 (0.956 -1.356)‡ |
<0.001 |
0.974 (0.807-1.175)‡ |
<0.001 |
| European |
5 |
1.143 (0.660-1.977)‡ |
0.043 |
0.988 (0.699-1.397)‡ |
0.021 |
1.101(0.776-1.562)‡ |
0.029 |
1.015 (0.763 -1.351) |
0.154 |
0.951 (0.745-1.213) |
0.053 |
| Source of Control |
|
|
|
|
|
|
|
|
|
|
|
| Population-based |
5 |
1.169 (0.694-1.970)‡ |
<0.001 |
1.156 (0.873-1.530)‡ |
0.029 |
1.170(0.800-1.712)‡ |
<0.001 |
0.965 (0.678-1.373)‡ |
<0.001 |
1.063 (0.802-1.408)‡ |
<0.001 |
| Hospital-based |
12 |
1.255 (0.901-1.749)‡ |
0.001 |
1.125 (0.828-1.530)‡ |
<0.001 |
1.154(0.864-1.541)‡ |
<0.001 |
1.257 (1.129-1.399） |
0.150 |
0.919 (0.778-1.086)‡ |
<0.001 |
Abbreviations: CI, confidence interval; OR, odds ratio.
* Studies of comparison,﹩P-value of Q-test for heterogeneity test, ‡ Random model was used. |
