Parameters

Test

Reference

P value^ψ

90 %CI^φ
(80-125 %)

T/R ratio

C_max (µg/ml)

10.058±0.318

10.398±0.258

0.21

98.72-102.16

96.47

T_max (h)

1.42±0.164

1.38±0.065

0.89

K_ele (l/hr)

0.274±0.028

0.255±0.028

0.50

T_1/2 (h)

2.862±0.311

3.093±0.318

0.50

AUC_0-t (µg.h/ml)

49.09±2.63

50.603±2.725

0.44

101.23-103.33

97.15

AUC_0-inf  (µg.h/ml)

50.925±2.77

53.584±2.94

0.20

101.18-104.64

95.16