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Figure 2: Plasma dihydroartemisinin concentration-time profiles after administration of single oral doses of artesunate and mefloquine given as a Fixed formulation (200 mg artesunate/400 mg mefloquine) or a Non- Fixed formulation (200 mg artesunate + 500 mg mefloquine) to healthy volunteers (n=24). Data expressed as mean ± standard error of the mean. |