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| Figure 7: Plasma mefloquine concentration-time profiles after administration of multiple oral doses of artesunate and mefloquine given as a Fixed formulation (200 mg artesunate/400 mg mefloquine daily for 3 days) or a Non-Fixed formulation (4 mg/kg artesunate + 0 mg/kg mefloquine on Day 1; 4 mg/kg artesunate + 15 mg/kg mefloquine on Day 2; 4 mg/kg artesunate + 10 mg/kg mefloquine on Day 3) to uncomplicated falciparum malaria patients (Fixed: n=20; Non-Fixed: n=23). Data expressed as mean ± standard error of the mean. |
