Drug

Extraction method

Linearity range
ng/mL

Internal standard

Plasma volume for extraction

Bicalutamide

Solid phase

10.038-1500.183

Nimesulide

0.2 mL

Topiramate

Solid phase

50.040-3002.396

Phenytoin

0.5 mL

Amitriptyline

Solid phase

0.814-81.401

Imipramine

0.2 mL