Drug
Parameter
Partial AUC0- 72
Partial AUC0-2 X t/2
Baseline value (total AUC)
Bicalutamide N = 39
CI_90_Lower
85.89
83.53
86.00
CI_90_Upper
99.57
95.63
96.13
Ratio[%Ref]
92.48
89.37
91.08
Topiramate N=26
99.1
98.45
98.23
103.86
103.42
102.68
101.45
100.9
100.43
Amitryptiline N=24
95.14
*
95.79
109.59
110.45
102.11
102.86
* Not applicable as T1/2 hrs х 2 is less than 72 hrs
Table 2: Study results after AUC truncation at different time points
