Parameters
Test preparation
Reference preparation
Cmax (μg/ml)
1.52±0.48
1.42±0.39
T
max
(h)
3.08±0.73
3.22±0.81
t
1/2
(h)
2.04±0.53
1.87±0.29
AUC
0-t
(μg/ml•h
-1
)
7.12±1.85
6.86±1.60
AUC0
0-∞
(μg/ml•h
-1
)
7.67±2.01
7.38±1.85
F
0-t
(%)
103.53±11.50
F
0-∝
(%)
104.13±11.83
Table 1:
Main pharmacokinetic parameters of cefdinir after a single oral dose of 200mg cefdinir test and reference preparations in healthy Chinese male volunteers (n=18, mean±SD).
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