TEST REFERENCE  
Parameter (unit) Means
(Median)
Standard
Deviation
(Amplitude)
Means
(Median)
Standard
Deviation
(Amplitude)
AUC0-t (ng.h/mL) 412.20 217.26 432.41 259.23
AUC0-inf (ng.h/mL) 418.90 218.22 440.06 260.24
Cmax (ng/mL) 108.71 41.63 126.94 67.80
Tmax (median/amp) (h) 1.00 3.50 1.00 2.50
Kel (1/h) 0.14 0.05 0.14 0.05
T½ (median/amp) (h) 5.38 7.19 5.52 17.07
Table 1: Mean pharmacokinetic parameters of quetiapine of test and reference formulation
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