Oranor® coated tablet 400 mg (A) vs Noroxin® tablets 400 mg (B) Cmax AUC0-24ht AUC0- α Criteria equivalence
Schüirmann’s two one-sided t-test
p<80%
p>125%
0.0044
0.0007
0.0030
0.0000
0.0026
0.0000
  ≤ 0.05
CI 90% for the ratio of the parameters 87.06-108.32 85.55-100.19 85.75-100.22   80%-120%
Power 0.9277 0.9966 0.9970 > 0.80
Table 3: Schüirmann’s two one-sided t-test, 90% Confidence Interval (CI 90%) and Power of Norfloxacin pharmacokinetic parameters (non transformed) n = 26.
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