clopidogrel

SR26334

Parameter

Test

Reference

Test

Reference

Cmax, ng/mL

1.86(1.52)

1.97 (1.92)

2993 (962)

3328(807)

Tmax, h

0.6 ( 0.3)

0.7 ( 0.3)

0.68(0.20)

0.60(0.13)

t1/2, h

6.9 ( 6.5)

6.5 ( 6.0)

8.3(1.4)

7.7(1.2)

AUC0-t, ng∙h/mL

2.37 (1.66)

2.36 (1.54)

8108(1861)

8475(1493)

AUC0-∞, ng∙h/mL

2.48 (1.79)

2.43 (1.62)

8269(1690)

8624(1622)

Table 1: Pharmacokinetic properties of clopidogrel and SR26334 after a single 75-mg oral dose of 2 formulations of clopidogrel tablets in healthy Chinese male volunteers (n = 20). Data are mean (SD).
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