Pharmacokinetic parameters

Reference

Test

Cmax (ng/mL)

21.6 ± 5.1

21.8 ± 6.0

Tmax (h)

7.8 ± 3.2

6.4 ± 2.2

AUC0-t (ng.h/mL)

875.6 ± 167.3

865.6 ± 176.3

AUC0-inf (ng.h/mL)

1313.2 ± 274.4

1422.4 ± 388.5

t1/2 (h)

42.7 ± 12.1

52.2 ± 19.8

Table 1: Pharmacokinetic parameters (mean ± standard deviation) of memantine after the oral administration of single dose of reference and test formulations (n = 24).
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