Pharmacokinetic parameters (mean (SD)) of lamotrigine

Parameter	Test product	Reference Product
C_max (µg/mL)	2.226 (0.355)	2.314 (0.414)
T_max (h)	1.380 (1.060)	0.933 (0.729)
k_e (h)	0.020 (0.004)	0.021 (0.005)
t_1/2 (h)	36.261 (6.801)	35.694 (9.476)
AUC_0-120 (µg/mL)× h	69.277 (13.432)	70.148 (10.824)
AUC_0-∞ (µg/mL)× h	77.532 (15.255)	78.524 (16.000)

Table 2: Pharmacokinetic parameters (mean (SD)) of lamotrigine after a single 100 mg oral dose of the two products in healthy Colombian volunteers (n=12).

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