Parameter
Test Formulation
Reference Formulation
Geometric mean Cmax (ng/mL) range
534.67 193.87 – 1423.04
567.82 298.80 – 1585.02
Geometric mean AUC0-t ngxh/ml) Range
4443.48 2178.76 – 8148.69
4695.61 2452.39 – 8203.54
Geometric mean AUC0-∞ (ngxh/ml) Range
5075.61 2615.24 – 9154.81
5323.31 2722.78 – 9340.76
Geometric mean t1/2 (h) range
49.99 36.29 – 65.73
47.40 36.63 – 63.81
Median tmax (h) range
1.75 1.00 – 6.00
2.25 1.00 – 4.00
