Time (hours)   IR F-1* (10%) F-2* (20%) F-3* (30%) F-4* (40%) F-5* (50%) 0 0 0 0 0 0 0 0.25 74.23 - - - - - 0.5 105.12 18.8 20 22.43 7.67 4.30 0.75 107.25 - - - - - 1.0 109.23 37.7 40.14 27.87 15.45 11.27 1.5 - 56.62 45.66 55.44 23.5 18.12 2.0 - 75.47 50.11 79.56 31.9 22.16 2.5 - 94.45 60.12 95.17 39.1 25.29 3.0 - 94.12 94.11 99.12 46.99 30.71 4.0 - 94.22 90.46 93.11 58.8 66.37 6.0 - 94.5 91.75 89.83 74.5 75.23 8.0 - 94.40 91.75 94.52 84.91 77.39 10.0 - - - - 91 78.9 12.0 - - - - 93.7 78.8 18.0 - - - - 93.6 78.5 24.0 - - - - 93.7 78.5 *All values represent mean (n=6)±SD

Table 3: In vitro release profile of Losartan Potassium from Xanthan gum matrices (IR and F-1 to F-5).

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