INGREDIENTS F1 F2 F3 F4 F5 F6 F7 F8
Phenytoin sodium 100 100 100 100 100 100 100 100
Avicel PH101 - - - 55.15 54.3 54.2 - -
Ethyl cellulose N-14 (14 cps) - - - 4.25 8.5 7.5 - -
HPMC - - - - - 5.5   -
HPMC-E15 - - -   5.3 - - -
HPMC- K4M - - - - - - 40  
Chitosan - - - - - - - 40
Eudragit RSPO 30 - - - - - - -
Eudragit RS100 -   30 8.5 - - - -
Eudragit RL100 - 30 - - - - -  
Lactose 1.5 2 6.5   - - 1.6 1.6
Mg.stearate 1.5 1.8 2 1.7 1.7 1.5 1.5 1.5
Talc 0.6 5.5 7   - - 0.6 0.6
Colloidal
silicone dioxide
-     0.4 0.6 0.8 - -
Starch 5% 5% 5% - - - - -
Purified water q.s q.s q.s q.s q.s q.s q.s q.s
SLS 7.5 7.5 6.5 3.25 6.5 7.5 3.25 6.5
F1, F2 and F3 formulations contain processed starch in percentage of 5%.
F5 and F6 formulations contain colloidal silicon dioxide in the percentage of 0.5-1%.
F5 and F6 formulations contain Avicel PH101 in the percentage of 53-55%.
Table 1: Tablet Formulations.
Goto home»