Midazolam n=28

Desvenlafaxine 50 mg n=28

Desvenlafaxine + Midazolam n=28

Any adverse event, n (%)

21 (75.0)

16 (57.1)

24 (85.7)

Somnolence

20 (71.4)

0

20 (71.4)

Abdominal pain

1 (3.6)

4 (14.3)

0

Decreased appetite

0

2 (7.1)

0

Diarrhea

0

2 (7.1)

0

Fatigue

0

3 (10.7)

4 (14.3)

Feeling abnormal

0

2 (7.1)

0

Headache

0

6 (21.4)

1 (3.6)

Insomnia

0

3 (10.7)

1 (3.6)

Nausea

0

3 (10.7)

0