| Parameter |
Unit |
N |
Mean |
SD |
Min |
Median |
Max |
CV% |
| AUCinf |
([ng*hr]/mL) |
20 |
2467 |
765 |
839 |
2632 |
3496 |
30.99 |
| AUClast |
([ng*hr]/mL) |
20 |
2044 |
641 |
729 |
2249 |
3218 |
31.36 |
| Clast |
(ng/mL) |
20 |
7.74 |
3.20 |
5.13 |
6.62 |
19.30 |
41.26 |
| Cmax |
(ng/mL) |
20 |
119.49 |
25.09 |
71.70 |
119.50 |
177.00 |
21.00 |
| Ke |
(1/hr) |
20 |
0.02 |
0.01 |
0.01 |
0.02 |
0.06 |
60.21 |
| T1/2 |
(hr) |
20 |
38.08 |
15.88 |
12.10 |
40.65 |
71.47 |
41.69 |
| Tlast |
(hr) |
20 |
90.00 |
24.47 |
48.00 |
96.00 |
120.00 |
27.19 |
| Tmax |
(hr) |
20 |
2.65 |
1.23 |
1.00 |
2.50 |
6.00 |
46.26 |
| Vd |
(L) |
20 |
111.71 |
33.42 |
54.68 |
114.00 |
164.42 |
29.91 |
| CL |
(L/hr) |
20 |
2.34 |
1.14 |
1.43 |
1.90 |
5.96 |
48.96 |
|
