| |
Desvenlafaxine 200-mg dose |
Desvenlafaxine 300-mg dose |
| |
Young
(18–45 years) |
Elderly
(65–75 years) |
Very old
(>75 years) |
Young (18–45 years) |
Elderly
(65–75 years) |
Very old
(>75 years) |
|
Characteristic |
Men
(n=5) |
Women
(n=8) |
Men
(n=4) |
Women
(n=6) |
Men
(n=7) |
Women
(n=8) |
Men
(n=3) |
Men
(n=3) |
Women
(n=2) |
Men
(n=2) |
| Age, years |
|
|
|
|
|
|
|
|
|
|
| Mean (SD) |
29.6 (7.1) |
38.0 (5.1) |
68.8 (3.6) |
68.8 (2.7) |
76.9 (1.2) |
77.9 (2.4) |
37.7 (5.5) |
71.7 (1.2) |
73.0 (0.0) |
82.0 (1.4) |
| Minimum,
maximum |
23.0, 39.0 |
29.0, 44.0 |
66.0, 74.0 |
66.0, 72.0 |
76.0, 79.0 |
75.0, 81.0 |
32.0, 43.0 |
71.0, 73.0 |
73.0, 73.0 |
81.0, 83.0 |
| Race,
n (%) |
|
|
|
|
|
|
|
|
|
|
| Black |
3 (60) |
1 (13) |
|
|
|
|
|
|
|
|
| Other |
1 (20) |
1 (13) |
1 (25) |
5 (83) |
|
1 (13) |
|
|
|
|
| White |
1 (20) |
6 (75) |
3 (75) |
1 (17) |
7 (100) |
7 (88) |
3 (100) |
3 (100) |
2 (100) |
2 (100) |
| Height, cm |
|
|
|
|
|
|
|
|
|
|
| Mean (SD) |
178.5 (5.7) |
157.3 (7.5) |
165.6 (3.8) |
158.8 (7.5) |
170.3 (5.0) |
157.0 (6.4) |
183.8 (9.4) |
177.8 (12.0) |
159.0 (1.2) |
167.7 (2.8) |
| Minimum,
maximum |
170.0, 183.5 |
140.0, 165.0 |
160.0, 168.0 |
147.0, 168.0 |
165.0, 180.1 |
145.0, 165.0 |
172.9, 189.4 |
169.1, 191.5 |
158.1, 159.8 |
165.7, 169.7 |
| Weight, kg |
|
|
|
|
|
|
|
|
|
|
| Mean (SD) |
86.8 (11.1) |
62.9 (10.3) |
69.9 (5.7) |
67.3 (9.2) |
77.6 (13.2) |
63.0 (7.3) |
85.5 (9.8) |
89.7 (17.6) |
57.2 (6.5) |
77.4 (14.9) |
| Minimum,
maximum |
73.8, 100.2 |
45.4, 76.4 |
62.8, 75.9 |
56.4, 78.2 |
58.6, 91.8 |
49.1, 71.4 |
74.8, 94.1 |
74.2, 108.8 |
52.6, 61.8 |
66.8, 87.9 |
|
