| Parameter |
Test Formulation |
Reference Formulation |
| Cmax (ng/mL) |
|
|
| Geometric Mean |
61.79 |
61.74 |
| Range |
32.82-104.34 |
35.86-105.54 |
| AUC0-t (ngxh/mL) |
|
|
| Geometric Mean |
762.09 |
762.94 |
| Range |
369.13-1435.91 |
393.68-1426.05 |
| AUC0-∞ (ngxh/mL) |
|
|
| Geometric Mean |
771.87 |
772.62 |
| Range |
374.11-1458.57 |
397.46-1465.44 |
| t1/2(h) |
|
|
| Geometric Mean |
6.46 |
6.42 |
| Range |
4.51-10.41 |
4.56-8.54 |
| tmax(h) |
|
|
| Median |
5.00 |
5.00 |
| Range |
3.00-8.00 |
3.00-7.00 |
|
