two enteric coated formulations

Products	C_max (µg/mL)	T_max (h)	T_½(h)	AUC_ult (µg.h/mL)	AUC_tot (µg.h/mL)
Test	46.5 ± 6.8	6.3 ± 1.9	15.7 ± 4.9	853.4 ± 177.2	923.9 ± 215.4
Reference	44.2 ± 6.7	9.6 ± 5.9	15.3 ± 4.2	902.1 ± 213.5	969.3 ± 246.0

Table 2: Peak plasma valproic acid levels (C_max), time to achieve C_max (T_max), plasma elimination half-life (T_½), and area under the curve 0-24 hrs (AUC_ult) and extrapolated to infinite (AUC_tot), after the intake of two enteric coated formulations (test and reference) containing each one 500mg of sodium divalproate, single dose, by 24 healthy men.Figures are mean and SD.

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