Phospate Conc. (mM) |
Tablet |
Pioglitazone Conc. (µg/mL) |
3.125 |
4.25 |
6.25 |
3.82 |
12.5 |
4.27 |
25 |
3.11 |
50 |
1.78 |
The pioglitazone tablet was placed in 200 mL of various concentration of phosphate
buffer (pH 6.5).The flasks were incubated at 37°C for 4 hours. The concentration
of pioglitazone was determined by HPLC analysis. Values presented are the
mean(n=3). |