Phospate Conc. (mM) Tablet
Pioglitazone Conc. (µg/mL)
3.125 4.25
6.25 3.82
12.5 4.27
25 3.11
50 1.78
The pioglitazone tablet was placed in 200 mL of various concentration of phosphate buffer (pH 6.5).The flasks were incubated at 37°C for 4 hours. The concentration of pioglitazone was determined by HPLC analysis. Values presented are the mean(n=3).
Table 1: The solubility study of pioglitazone in the different concentration of phosphate buffer (pH 6.5).
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