| Plasma Aripiprazole
Parameter (units) |
Adjusted Geometric Means |
Ratio (Test/Reference)
of Adjusted Means* |
90% CI
for Ratio |
| Aripiprazole 5 mg With Desvenlafaxine 100 mg QD (Test) |
Aripiprazole
5 mg
(Reference) |
| AUCinf (ng•h/mL) |
1584 |
1494 |
105.97 |
101.39, 110.76 |
| AUClast (ng•h/mL) |
1465 |
1377 |
106.38 |
101.96, 110.99 |
| Cmax (ng/mL) |
24.92 |
24.66 |
101.05 |
92.94, 109.87 |
AUCinf= area under the plasma concentration curve over infinite time; AUClast= area under the plasma concentration curve to the last measurable concentration; CI=
confidence interval; Cmax = peak plasma concentration; QD= once daily
*The ratios (and 90% CIs) are expressed as percentages |
