| Plasma Aripiprazole Parameter (units) |
Adjusted Geometric Means |
Ratio (Test/Reference) of Adjusted Means* |
90% CI for Ratio |
| Aripiprazole 5 mg With Desvenlafaxine 100 mg QD (Test) |
Aripiprazole 5 mg (Reference) |
| AUCinf (ng•h/mL) |
699.2 |
679.3 |
102.93 |
94.21, 112.46 |
| AUClast (ng•h/mL) |
630.9 |
599.6 |
105.23 |
101.32, 109.29 |
| Cmax (ng/mL) |
3.195 |
3.007 |
106.27 |
100.97, 111.85 |
AUCinf= area under the plasma concentration curve over infinite time; AUClast= area under the plasma concentration curve to the last measurable concentration; CI=
confidence interval; Cmax = peak plasma concentration; QD= once daily
*The ratios (and 90% CIs) are expressed as percentages |
