| Cell lines |
Curcumin (μM) |
Curcumin liposome (μM) |
Curcumin/LPPC (μM) |
| Mouse |
|
|
|
| B16/F10 |
8.2 ± 1.0† |
7.8 ± 1.3 |
1.1 ± 0.1 |
| LL-2 |
10.8 ± 2.3 |
9.9 ± 0.1 |
1.4 ± 0.2 |
| CT-26 |
7.9 ± 0.8 |
6.8 ± 0.8 |
1.2 ± 0.1 |
| JC |
11.0 ± 1.5 |
9.3 ± 0.1 |
1.3 ± 0.1 |
| Human |
|
|
|
| HepG2 |
12.2 ± 1.1 |
10.0 ± 0.4 |
1.7 ± 0.2 |
| HT-29 |
12.9 ± 1.2 |
10.9 ± 1.0 |
1.5 ± 0.1 |
| HeLa |
17.7 ± 7.0 |
10.0 ± 0.2 |
1.2 ± 0.2 |
| Curcumin-resistant cells |
|
|
| A549 |
30.0 ± 9.5 |
12.5 ± 0.4 |
1.4 ± 0.1 |
| CT26/cur-r |
27.3 ± 4.6 |
ND |
1.3 ± 0.1 |
| B16F10/cur-r |
24.0 ± 8.5 |
ND |
1.3 ± 0.2 |
|
Normal cells |
|
|
|
| PBMC |
15.2 ± 4.1 |
ND |
9.9 ± 1.1 |
| MS1 |
21.1 ± 6.4 |
ND |
11.7 ± 1.5 |
| SVEC4-10 |
15.7 ± 3.7 |
ND |
9.0 ± 0.5 |
*Inhibition of cells exposed to IC50 levels of curcumin
ND: non-detection
†: All values are mean ± SD of 3 independent experiments (n=6)
|
