Parameter Test Reference
Mean CV% Mean CV%
Cmax (ng/mL) 1108.89 28 1073.06 35
Tmax (hours) 2.22 37.99 3.48 162.49
AUC0-T (ng·h/mL) 23764.87 31 24607.87 33
AUC0-∞ (ng·h/mL) 25489.41 36 26565.89 40
AUCT/∞ (%) 94.64 5.49 93.95 7.28
Kel (hours-1) 0.0603 56.74 0.0597 52.44
T½el (hours) 14.33 43.87 14.67 48.08
Table 2: The Pharmacokinetic Parameters of Erlotinib tablets 150 mg versus Tarceva.
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